Peer-reviewed trials, cohort studies, and meta-analyses — filterable by condition, pressure, and study type. Every record links to DOI or PubMed.
This 162-patient cohort study extended and confirmed the original Efrati 2013 finding: HBOT can drive neuroplasticity in chronic post-stroke patients, even decades after the original event. Patients in this cohort were 6 …
Bennett et al. (2016, Cochrane Database of Systematic Reviews) is the cornerstone of the evidence base for HBOT in cancer survivorship — specifically for late radiation tissue injury (LRTI), one of HBOT's …
Hadanny et al. (2018, International Journal of Impotence Research) is the first published trial to demonstrate mechanism-level vascular repair from HBOT in vasculogenic erectile dysfunction — meaning HBOT was shown not just …
Zilberman-Itskovich et al. (2022, Scientific Reports) is the trial that put HBOT for Long COVID on the published-evidence map. It is a randomized, double-blind, sham-controlled clinical trial — the strongest single design …
This trial focused on the acute, intensive-care-unit phase of severe traumatic brain injury — a very different population from chronic TBI. Even in this critically ill cohort, HBOT at 1.5 ATA reduced …
This preclinical study in a mouse model of Alzheimer's disease showed something striking: HBOT reduced amyloid plaque burden and improved cognition. While preclinical work doesn't guarantee human results, it provides mechanistic support …
Hadanny et al. (2020, Aging) is the cornerstone trial for HBOT as a cognitive-enhancement intervention in healthy older adults — distinct from injury-recovery use cases like TBI or stroke. What the trial …
Dr. Stephen Thom's research at the University of Pennsylvania revealed something remarkable: HBOT mobilizes your own stem cells from bone marrow into circulation. After a single session, CD34+ stem cell counts in …
Lin et al. 2023 is the most recent Cochrane Database update on HBOT for late radiation tissue injury (LRTI), succeeding Bennett et al. 2016 (pub4). The Cochrane Database of Systematic Reviews is …
This widely-cited multicenter trial enrolled 62 children with autism in a double-blind protocol. The treatment group received 1.3 ATA — the lowest pressure typically used clinically. Even at this gentle pressure with …
Tal et al. (2017, Frontiers in Human Neuroscience) is a Sagol Center cohort study examining whether HBOT can induce cerebral angiogenesis (new blood vessel formation) and regenerate nerve fibers in patients with …
Branco et al. (2016, PLOS One) is one of the few placebo-controlled HBOT studies in trained athletes — and it returned a NULL finding. Saturate's site philosophy holds that null findings are …
Efrati et al. (2015, PLoS ONE) is a prospective, active-control crossover trial of HBOT for fibromyalgia syndrome (FMS) in 60 female patients aged 21–67 who had been diagnosed with FMS for at …
Hachmo et al. (2020, Aging) made international headlines because it was the first published human trial to show that a non-pharmacological intervention could lengthen telomeres and clear out senescent cells — two …
Harch et al. (2017, Medical Gas Research) is a case-control study of HBOT for mild traumatic brain injury persistent post-concussion syndrome and post-traumatic stress disorder. The paper is one of Dr. Paul …
Efrati et al. (2013, PLOS One) is the trial that fundamentally challenged the prevailing view that stroke recovery has a fixed window of 6 months post-event. The paper's title — 'Hyperbaric oxygen …