Hyperbaric Oxygen Therapy Can Induce Angiogenesis and Regeneration of Nerve Fibers in Traumatic Brain Injury Patients

Tal S, Hadanny A, Sasson E, Suzin G, Efrati S

Frontiers in Human Neuroscience 2 ATA 60 sessions

Plain English

Tal et al. (2017, Frontiers in Human Neuroscience) is a Sagol Center cohort study examining whether HBOT can induce cerebral angiogenesis (new blood vessel formation) and regenerate nerve fibers in patients with prolonged post-concussion syndrome from traumatic brain injury. The paper's headline contribution is the imaging-confirmed structural finding: HBOT was associated with measurable improvements in both white and gray matter microstructure, interpreted by the authors as nerve-fiber regeneration. Prior Saturate copy attributed PTSD-focused n=154 DTI findings to this paper — those findings are from a different publication and have been retired here. The bibliographic record is now PubMed-verified; the long-form summary will be rewritten in the next verified-fetch pass. Source: PubMed PMID 29097988.

Key findings

What the trial documented.

HBOT can induce cerebral angiogenesis and improve white and gray microstructures, indicating regeneration of nerve fibers
Findings observed in patients with prolonged post-concussion syndrome from traumatic brain injury
Published in Frontiers in Human Neuroscience, 2017 — see PubMed PMID 29097988 for full abstract

Tal et al. (2017, Frontiers in Human Neuroscience) is a Sagol Center cohort study examining whether HBOT can induce cerebral angiogenesis (new blood vessel formation) and regenerate nerve fibers in patients with prolonged post-concussion syndrome from traumatic brain injury. The paper’s headline contribution is the imaging-confirmed structural finding: HBOT was associated with measurable improvements in both white and gray matter microstructure, interpreted by the authors as nerve-fiber regeneration. Prior Saturate copy attributed PTSD-focused n=154 DTI findings to this paper — those findings are from a different publication and have been retired here. The bibliographic record is now PubMed-verified; the long-form summary will be rewritten in the next verified-fetch pass.

Source: PubMed PMID 29097988.

Protocol used

Per published protocol — see PMID 29097988 for full method

Full citation

Tal S, Hadanny A, Sasson E, Suzin G, Efrati S. Hyperbaric Oxygen Therapy Can Induce Angiogenesis and Regeneration of Nerve Fibers in Traumatic Brain Injury Patients. Frontiers in Human Neuroscience. 2017.

DOI →