Dr. Stephen Thom’s research at the University of Pennsylvania revealed something remarkable: HBOT mobilizes your own stem cells from bone marrow into circulation. After a single session, CD34+ stem cell counts in the bloodstream doubled. After 20 sessions, they increased 8-fold. This is the mechanistic explanation for why HBOT helps with so many seemingly unrelated conditions — your own stem cells are being released to repair whatever is damaged. This 2006 paper is one of the most cited in the entire HBOT literature.
Cohort
2006
From the library
Stem cell mobilization by hyperbaric oxygen
Thom SR, Bhopale VM, Velazquez OC, Goldstein LJ, et al.
American Journal of Physiology — Heart and Circulatory Physiology n = 26 2 ATA 20 sessions
Plain English
Dr. Stephen Thom's research at the University of Pennsylvania revealed something remarkable: HBOT mobilizes your own stem cells from bone marrow into circulation. After a single session, CD34+ stem cell counts in the bloodstream doubled. After 20 sessions, they increased 8-fold. This is the mechanistic explanation for why HBOT helps with so many seemingly unrelated conditions — your own stem cells are being released to repair whatever is damaged. This 2006 paper is one of the most cited in the entire HBOT literature.
Key findings
What the trial documented.
- Single HBOT session doubled circulating stem cells (CD34+ cells)
- After 20 sessions, stem cell counts increased 8-fold
- Effect mediated by nitric oxide synthesis in bone marrow
- Established the mechanistic foundation for HBOT in regenerative medicine
Protocol used
2.0 ATA, 100% oxygen, 90-minute sessions, 5 days/week for 20 sessions
Full citation
Thom SR, Bhopale VM, Velazquez OC, Goldstein LJ, et al.. Stem cell mobilization by hyperbaric oxygen. American Journal of Physiology — Heart and Circulatory Physiology. 2006.